Where squamous cell carcinoma originates

Squamous cell carcinoma is the second most common form of skin cancer after basal cell carcinoma. Where squamous cell carcinoma originates? It is considered locally invasive, and, although uncommon, can spread beyond the skin into other organs of the body if left untreated. The cancer develops from squamous cells which are thin, flat cells found on the surface of the skin, in the lining of hollow organs and in the respiratory and digestive tracts. 
Where squamous cell carcinoma originates

It usually shows up on areas of the skin that are exposed to the sun, such as the face, ears, lips, arms, legs, and tops of hands, but it can also more rarely appear on areas not exposed to the sun, including the lower lip, genitals, lungs, and esophagus.

How does squamous cell carcinoma form?

Squamous cell carcinoma occurs when squamous cells begin to grow uncontrollably in the top layers of the skin, known as the epidermis.

This uncontrolled growth is usually a result of cellular damage often caused by chronic exposure to UV rays over time. This means that people who use tanning beds or who have spent a lot of time outdoors unprotected are at a much higher risk of developing squamous cell carcinoma as well as those with pale skin types.

Cellular damage can also more rarely be caused by other factors such as exposure to toxic substances or a weakened immune system. This puts people who have a history of actinic keratosis, those who have had some form of the human papillomavirus or have been badly burned in the past at a higher risk for developing the cancer as well.

What does a normal mole look like?

Where does squamous cell carcinoma form?

Researchers have been working to determine which cells trigger squamous cell carcinoma to form. Some evidence points to hair follicle stem cells as the origin point. Looking even closer, within these cells, researchers from UCLA discovered that the mother stem cells can develop the cancer while the progeny cells cannot.

This distinction between two different types of cells in the skin is providing researchers with new research targets. Looking into why one cell can develop the cancer and the other cannot is a potential avenue to treatments that may be able to prevent the cancer before it starts.

If you have any suspicions about a mole, spot or growth, have it checked out as soon as possible. 

Share this post:
Share on facebook
Share on linkedin
Share on whatsapp

Keep your skin healthy and find skin cancer early.

Peace of mind with an accurate risk indication.

Immediate response based on machine learning technology.

Find skin cancer early. It can save your life.

More about this topic:

How to prevent squamous cell carcinoma

How to prevent squamous cell carcinoma (SCC) | 5 steps

Squamous cell carcinoma (SCC) is one of the most common forms of skin cancer, affecting more than one million people in the US alone each year. While it is usually easily treatable, it can become deadly if it spreads beyond the skin and into the lymph nodes or internal organs of the body. That’s why prevention is so important.

How to prevent squamous cell carcinoma? Read it below.

Where is squamous cell carcinoma found?

Where is squamous cell carcinoma found?

As you might already know, squamous cell carcinoma is one of the most common types of skin cancer. While squamous cell carcinoma can be treated very well when found early, this type of skin cancer also has the potential to spread to the lymph nodes. In that case, it becomes very dangerous. At first squamous cell carcinoma will often appear as a scaly lump, a red scaly sunspot, or a crusted sore. But where is it commonly found?

Squamous cell carcinoma symptoms

Squamous cell carcinoma symptoms (SCC)

Most of us are aware of the usual signs of skin cancers – moles that look strange or start to change in shape or become itchy or crusty. But squamous cell carcinoma is a different type of skin cancer that looks unusual compared to those we might be on the lookout for. Squamous cell carcinoma symptoms may be harder to spot, but it is still possible to see clearly the signs and to catch it before it becomes harder to treat.

Squamous Cell Carcinoma: what is it?

Squamous cell carcinoma is the second most common type of skin cancer. It forms when squamous cells begin to grow uncontrollably in the top layers of the skin, called the epidermis. In most cases, it is caused by repeated exposure to UV rays over time.